Development of an immunogen containing CD4+/CD8+ T-cell epitopes for the prophylaxis of tegumentary leishmaniasis

Author:

de Andrade Ferraz Isabela,Carvalho Ana Maria Ravena Severino,de Brito Rory Cristiane Fortes,Roatt Bruno Mendes,Martins Vívian Tamietti,Lage Daniela Pagliara,dos Reis Cruz Luiza,Medeiros Fernanda Alvarenga Cardoso,Gonçalves Denise Utsch,da Costa Rocha Manoel Otávio,Coelho Eduardo Antonio Ferraz,de Oliveira Mendes Tiago Antônio,Duarte Mariana Costa,Menezes-Souza DanielORCID

Funder

CAPES

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference53 articles.

1. Alexander J, Brombacher F (2012) T helper1/T helper2 cells and resistance/susceptibility to Leishmania infection: is this paradigm still relevant? Front Immunol 3:80. https://doi.org/10.3389/fimmu.2012.00080

2. Alvar J, Velez ID, Bern C, Herrero M, Desjeux P, Cano J, Jannin J, den Boer M, Team WHOLC (2012) Leishmaniasis worldwide and global estimates of its incidence. PLoS One 7(5):e35671. https://doi.org/10.1371/journal.pone.0035671

3. Bakker AH, Hoppes R, Linnemann C, Toebes M, Rodenko B, Berkers CR, Hadrup SR, van Esch WJ, Heemskerk MH, Ovaa H, Schumacher TN (2008) Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. Proc Natl Acad Sci USA 105(10):3825–3830. https://doi.org/10.1073/pnas.0709717105

4. Brito RCF, Ruiz JC, Cardoso JMO, Ostolin T, Reis LES, Mathias FAS, Aguiar-Soares RDO, Roatt BM, Correa-Oliveira R, Resende DM, Reis AB (2020) Chimeric vaccines designed by immunoinformatics-activated polyfunctional and memory T cells that trigger protection against experimental visceral leishmaniasis. Vaccines 8(2). https://doi.org/10.3390/vaccines8020252

5. Brito RCFd (2018) Tese de Doutorado: Emprego da vacinologia reversa para a identificação, triagem e avaliação de peptídeos de L. infantum para o desenho e desenvolvimento de vacinas poliepítopos e de coquetel de peptídeos contra a leishmaniose visceral. Repositório Institucional da UFOP/EFAR/CIPHARMA. https://www.repositorio.ufop.br/handle/123456789/11659

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