Abstract
AbstractInstrumental neutron activation analysis (INAA) was employed to assay 32 minor and trace elements in bone of Bohemian Duke John of Görlitz (1370–1396) who suddenly died at the age 25 years for unknown reasons. Recently, histological examination of his illium bone was carried out, accompanied by histochemical staining reactions to learn about his health status. The INAA results disproved an elevated Al content indicated by the staining reaction with aluminon, but revealed elevated levels of Mn, As, Sb, and especially of Ag compared with literature values. The results are discussed in terms of toxicity of the above elements, especially whether their elevated levels could be the reason for Duke´s sudden death.
Funder
Ministerstvo Školství, Mládeže a Tělovýchovy
Nuclear Physics Institute of the Czech Academy of Sciences
Publisher
Springer Science and Business Media LLC
Reference25 articles.
1. Povýšil C (2024) Patologické mikroskopické nálezy v kosterních pozůstatcích významných osobností české historie (Pathological microscopic findings in bone remains of significant personalities of the Czech history). Grada, Prague, ISBN978-80-271-5191-2 (in Czech)
2. Clark RC, Krueger GL (1985) Aluminon: its limited application as a reagent for the detection of aluminum species. J Histochem Cytochem 33:729–732
3. Krechlerová A, Košťál M, Milčák J, Kučera J (2024) Availability of neutron activation facilities to foreign users at research centre Řež, Czech Republic. J Radioanal Nuclear Chem 333(7):3559–3564. https://doi.org/10.1007/s10967-023-09276-7
4. Horák Z, Kučera J, Mizera J, Kameník J, Fikrle M (2024) Modernized control of a pneumatic facility for short-time NAA at LVR-15 reactor in Řež, Czech Republic. J Radioanal Nuclear Chem 333(7):3351–3357. https://doi.org/10.1007/s10967-023-09146-2
5. Řanda Z, Frána J, Mizera J et al (2007) Instrumental neutron and photon activation analysis in the geochemical study of phonolitic and trachytic rocks. Geostand Geaoanal Res 31:275–283