The Overlapping Thermodynamic Dissociation Constants of the Antidepressant Vortioxetine Using UV–VIS Multiwavelength pH-Titration Data

Author:

Meloun MilanORCID,Pilařová LucieORCID,Čápová AnetaORCID,Pekárek TomášORCID

Funder

No fund

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry,Molecular Biology,Biochemistry,Biophysics

Reference38 articles.

1. Lundbeck, H.: FDA accepts Takeda and Lundbeck’s filing for review of Brintellix (vortioxetine) for the treatment of major depression. http://investor.lundbeck.com/releasedetail.cfm?releaseid=726533 (2012)

2. Lundbeck, H.: BRINTELLIX™ (vortioxetine) tablets for oral use. Full Prescribing Information. Pharmacodynamics (2013)

3. Kelliny, M., Croarkin, P.E., Moore, K.M., Bobo, W.V.: Profile of vortioxetine in the treatment of major depressive disorder: an overview of the primary and secondary literature. Ther. Clin. Risk Manag. 11, 1193–1212 (2015)

4. Kohler, S., Cierpinsky, K., Kronenberg, G., Adli, M.: The serotonergic system in the neurobiology of depression: relevance for novel antidepressants. J. Psychopharm. 30(1), 13–22 (2016)

5. Rothschild, A.J., Mahableshwarkar, A.R., Jacobsen, P., Yan, M., Sheehan, D.V.: Vortioxetine (Lu AA21004) 5 mg in generalized anxiety disorder: results of an 8-week randomized, double-blind, placebo-controlled clinical trial in the United States. Eur. Neuropsychopharm. 22(12), 858–866 (2012)

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