Solvent Effects on the Structure-Activity Relationship of Pharmacological Active 3-Substituted-5,5-Diphenylhydantoins

Author:

Banjac Nebojša,Ušćumlić Gordana,Valentić Nataša,Mijin Dušan

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry,Molecular Biology,Biochemistry,Biophysics

Reference35 articles.

1. Lopez, A.C., Trigo, C.G.: In: Katrizky, A.R. (ed.) The Chemistry of Hydantoins. Advances in Heterocyclic Chemistry. Academic Press, New York (1985)

2. Scholl, S., Koch, A., Henning, D., Kempter, G., Kleinpeter, E.: The influence of structure and lipophilicity of hydantoin derivatives on anticonvulsant activity. Struct. Chem. 10, 355–366 (1999)

3. Knabe, J., Baldauf, J., Ahlhem, A.: Racemates and enantiomers of basic substituted 5-phenylhydantoins. Syntheses and antiarrhythmic activity. Pharmazie 52, 912–919 (1997)

4. Anger, T., Madge, D.J., Mulla, M., Riddall, D.: Medicinal chemistry of neuronal voltage-gated sodium channel blockers. J. Med. Chem. 44, 115–137 (2001)

5. Kleinpeter, E.: The structure of hydantoins in solution and in the solid state. Struct. Chem. 8, 161–173 (1997)

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