Total Neoadjuvant Therapy in Rectal Cancer: Multi-center Comparison of Induction Chemotherapy and Long-Course Chemoradiation Versus Short-Course Radiation and Consolidative Chemotherapy

Author:

Moyer Amber M.ORCID,Vogel Jon D.,Lai Samuel H.,Kim Hyun,Chin Re-I,Moskalenko Marina,Olsen Jeffrey R.,Birnbaum Elisa H.,Silviera Matthew L.,Mutch Matthew G.,Chapman Brandon C.

Publisher

Elsevier BV

Subject

Gastroenterology,Surgery

Reference29 articles.

1. Sauer R, Liersch T, Merkel S, Fietkau R, Hohenberger W, Hess C et al. Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2012;30(16):1926-33. https://doi.org/10.1200/jco.2011.40.1836.

2. van Gijn W, Marijnen CA, Nagtegaal ID, Kranenbarg EM, Putter H, Wiggers T et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer: 12-year follow-up of the multicentre, randomised controlled TME trial. The Lancet Oncology. 2011;12(6):575-82. https://doi.org/10.1016/s1470-2045(11)70097-3.

3. Chapman WC, Jr., Kim H, Bauer P, Makhdoom BA, Trikalinos NA, Pedersen KS et al. Total Neoadjuvant Therapy With Short-Course Radiation: US Experience of a Neoadjuvant Rectal Cancer Therapy. Dis Colon Rectum. 2022;65(2):198-206. https://doi.org/10.1097/dcr.0000000000001997.

4. Morris EJA, Finan PJ, Spencer K, Geh I, Crellin A, Quirke P et al. Wide Variation in the Use of Radiotherapy in the Management of Surgically Treated Rectal Cancer Across the English National Health Service. Clinical oncology (Royal College of Radiologists (Great Britain)). 2016;28(8):522–31. https://doi.org/10.1016/j.clon.2016.02.002.

5. Erlandsson J, Lörinc E, Ahlberg M, Pettersson D, Holm T, Glimelius B et al. Tumour regression after radiotherapy for rectal cancer - Results from the randomised Stockholm III trial. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2019;135:178-86. https://doi.org/10.1016/j.radonc.2019.03.016.

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