Primary Tumor Resection Following Favorable Response to Systemic Chemotherapy in Stage IV Pancreatic Adenocarcinoma with Synchronous Metastases: a Bi-institutional Analysis

Author:

Wright G. PaulORCID,Poruk Katherine E.,Zenati Mazen S.,Steve Jennifer,Bahary Nathan,Hogg Melissa E.,Zuriekat Amer H.,Wolfgang Christopher L.,Zeh Herbert J.,Weiss Matthew J.

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology,Surgery

Reference17 articles.

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2. Conroy T, Desseigne F, Ychou M, Bouché O, Guimbaud R, Bécouarn Y, Adenis A, Raoul JL, Gourgou-Bourgade S, de la Fouchardiere C, Bennouna J, Bachet JB, Kehmissa-Akouz F, Pere-Verge D, Delbaldo C, Assenat E, Chauffert B, Michel P, Montot-Grillot C, Ducreux M for the Groupe Tumeurs Digestives of Unicancer and the PRODIGE Intergroup. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med. 2011;364:1817-1825.

3. Von Hoff DD, Ervin T, Arena F, Chiorean EG, Infante J, Moore M, Seay T, Tjulandin SA, Ma WW, Saleh MN, Harris M, Reni M, Dowden S, Laheru D, Bahary N, Ramanathan RK, Tabernero J, Hidalgo M, Goldstein D, Van Custem E, Wei X, Iglesias J, Renschler MF. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. N Engl J Med. 2013;369:1691-1703.

4. Leal JN, Bressan AK, Vachharajani N, Gonen M, Kingham TP, D’Angelica MI, Allen PJ, DeMatteo RP, Doyle MB, Bathe OF, Greig PD, Wei A, Chapman WC, Dixon E, Jarnagin WR. Time-to-surgery and survival outcomes in resectable colorectal liver metastases: a multi-institutional evaluation. J Am Coll Surg. 2016;222:766-779.

5. Tarantino I, Warschkow R, Worni M, Cerny T, Ulrich A, Schmied BM, Guller U. Prognostic relevance of palliative primary tumor removal in 37,793 metastatic colorectal cancer patients: a population-based, propensity score-adjusted trend analysis. Ann Surg. 2015;262:112-120.

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