Neither Surgical Margin Status nor Somatic Mutation Predicts Local Recurrence After R0-intent Resection for Colorectal Liver Metastases

Author:

Nishioka Yujiro,Paez-Arango Natalia,Boettcher Federico Oppliger,Kawaguchi Yoshikuni,Newhook Timothy E.,Chun Yun Shin,Tzeng Ching-Wei D.,Tran Cao Hop S.,Lee Jeffrey E.,Vreeland Timothy J.,Vauthey Jean-NicolasORCID

Funder

national cancer institute

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology,Surgery

Reference30 articles.

1. Kopetz S, Vauthey JN. Perioperative chemotherapy for resectable hepatic metastases. Lancet (London, England). 2008;371(9617):963-5. https://doi.org/10.1016/s0140-6736(08)60429-8.

2. Vigano L, Costa G, Cimino MM, Procopio F, Donadon M, Del Fabbro D et al. R1 Resection for Colorectal Liver Metastases: a Survey Questioning Surgeons about Its Incidence, Clinical Impact, and Management. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2018;22(10):1752-63. https://doi.org/10.1007/s11605-018-3820-z.

3. Kokudo N, Miki Y, Sugai S, Yanagisawa A, Kato Y, Sakamoto Y et al. Genetic and histological assessment of surgical margins in resected liver metastases from colorectal carcinoma: minimum surgical margins for successful resection. Archives of surgery (Chicago, Ill : 1960). 2002;137(7):833–40. https://doi.org/10.1001/archsurg.137.7.833.

4. Pawlik TM, Scoggins CR, Zorzi D, Abdalla EK, Andres A, Eng C et al. Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases. Annals of surgery. 2005;241(5):715–22, discussion 22–4. https://doi.org/10.1097/01.sla.0000160703.75808.7d.

5. Holdhoff M, Schmidt K, Diehl F, Aggrawal N, Angenendt P, Romans K et al. Detection of tumor DNA at the margins of colorectal cancer liver metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research. 2011;17(11):3551-7. https://doi.org/10.1158/1078-0432.CCR-10-3087.

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