Abstract
AbstractBorate-doped silicate glasses with chemical compositions of (70 − x)SiO2–xB2O3–30CaO (x = 0, 5, 15, and 25, in mol%) were synthesized using the sol–gel method, intended to be used in tissue regeneration. The effects of borate content on the glass surface morphology, chemical structure, ion dissolution behavior, and fibroblast compatibility were investigated. 11B magic angle spinning-solid state nuclear magnetic resonance and Fourier transform infrared spectra demonstrated that borate, in the glasses, possessed both three- and four-coordinated structures. From nitrogen sorption, the specific surface area of the glasses decreased with increased borate content and calcination temperature, from 600 °C to 700 °C. In the case of glasses undergoing calcination at 700 °C, silicate and calcium ion released in a Tris–HCl buffer solution (pH = 7.4) at the early stage of the immersion test decreased as borate content increased. The decrease in surface area caused by stabilizing at 700 °C due to the effect of increasing borate concentration controlled the ion dissolution behavior of the glasses. The proliferation ability of fibroblasts cultured with the dissolution products of the glasses were improved as borate content increased in the glass composition.
Graphical Abstract
Funder
Japan Society for the Promotion of Science
Nippon Sheet Glass Foundation for Materials Science and Engineering
Hibi Science Foundation
Publisher
Springer Science and Business Media LLC
Subject
Materials Chemistry,Condensed Matter Physics,Biomaterials,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献