Interactions of bupranolol with the polymorphic debrisoquine/sparteine monooxygenase (CYP2D6)

Author:

Pressacco J.,Muller R.,Kalow W.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference27 articles.

1. Mahgoub A, Idle JR, Dring LG, Lancaster R, Smith RL (1977) Polymorphic hydroxylation of debrisoquine in man. Lancet II: 584?586

2. Eichelbaum M, Spannbrucker N, Steincke B, Dengler HJ (1979) Defective N-oxidation of sparteine in man: a new pharmacogenetic defect. Eur J Clin Pharmacol 16: 183?187

3. Meyer UA, Skoda RC, Zanger UM (1992) The genetic polymorphism of debrisoquine/sparteine metabolism ? clinical aspects. In: Kalow W (ed) International Encyclopedia of Pharmacology and Therapeutics, Section 137: Pharmocogenetics of drug metabolism. Pergamon Press, New York Oxford, pp 609?623

4. Eichelbaum M, Gross AS (1992) The genetic polymorphism of debrisoquine/sparteine metabolism ? clinical aspects. In: Kalow W (ed) International Encyclopedia of Pharmacology and Therapeutics, Section 137: Pharmocogenetics of drug metabolism. Pergamon Press, New York Oxford, pp 625?648

5. Alvan G, von Bahr C, Seideman P, Sjoqvist F (1982) High plasma concentrations of beta-receptor blocking drugs and deficient debrisoquine hydroxylation. Lancet II: 333

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