Identifying exposures to ribosome-inactivating proteins in blood samples: amplification of ricin-induced ribosomal damage products enables sensitive detection of active toxin and circulating depurinated 28S rRNA-Reference-Cited by-同舟云学术

Identifying exposures to ribosome-inactivating proteins in blood samples: amplification of ricin-induced ribosomal damage products enables sensitive detection of active toxin and circulating depurinated 28S rRNA

Published:2018-04-11 Issue:2 Volume:36 Page:375-384
ISSN:1860-8965
Container-title:Forensic Toxicology
language:en
Short-container-title:Forensic Toxicol

Author:

Falach Reut,Israeli Ofir,Gal Yoav,Sapoznikov Anita,Shifman Ohad,Ehrlich Sharon,Aftalion Moshe,Beth-Din Adi,Sabo Tamar,Kronman Chanoch

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry, medical,Toxicology,Pathology and Forensic Medicine

Link

http://link.springer.com/article/10.1007/s11419-018-0414-0/fulltext.html

Reference45 articles.

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2. Kumar O, Sugendran K, Vijayaraghavan R (2003) Oxidative stress associated hepatic and renal toxicity induced by ricin in mice. Toxicon 41:333–338

3. Brinkworth CS (2010) Identification of ricin in crude and purified extracts from castor beans using on-target tryptic digestion and MALDI mass spectrometry. Anal Chem 82:5246–5252

4. Rutenber E, Ready M, Robertus JD (1987) Structure and evolution of ricin B chain. Nature 326:624–626

5. Olsnes S, Fernandez-Puentes C, Carrasco L, Vazquez D (1975) Ribosome inactivation by the toxic lectins abrin and ricin. Eur J Biochem 60:281–288

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