An in vitro study on the metabolic interaction between ethanol and caffeine at high concentrations using human liver microsomes

Author:

Nakamura Takako,Tanaka Einosuke,Honda Katsuya

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry, medical,Toxicology,Pathology and Forensic Medicine

Reference27 articles.

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2. Kalow W, Tang BK (1991) Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities. Clin Phamacol Ther 50:508–519

3. Butler MA, Iwasaki M, Guengerich FP, Kadlubar F (1989) Human cytochrome P450A (P-4501A2), the phenacetin, Odeethylase, is primarily responsible for the hepatic 3- demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proc Natl Acad Sci USA 86:7696–7700

4. Nowell S, Sweeney C, Hammons G, Kadlubar FF, Lang NP (2002) CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 11:377–383

5. Aklillu E, Carrillo JA, Makonnen E, Bertilsson L, Ingelman-Sundberg M (2003) Xanthine oxidase activity is influenced by environmental factors in Ethiopians. Eur J Clin Pharmacol 59:533–536

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1. Energiedranken en alcohol;Tijdschrift voor Kindergeneeskunde;2014-12

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