Identification of the designer benzodiazepine 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine (flualprazolam) in an anesthesia robbery case

Author:

Qian Zhenhua,Liu Cuimei,Huang Jian,Deng Qingqing,Hua Zhendong

Abstract

Abstract Purpose This publication reports analytical properties of the designer benzodiazepine 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine (flualprazolam) seized in an anesthesia robbery case. Methods The target compound was identified by liquid chromatography–quadrupole time-of-flight-mass spectrometry (LC–QTOF-MS), gas chromatography–mass spectrometry (GC–MS), and nuclear magnetic resonance (NMR) spectroscopy. Results We could obtain detailed analytical data of flualprazolam—a new designer benzodiazepine available on the designer drug market. Conclusions More designer benzodiazepines have been detected and seized on the illegal drug scene as new psychoactive substances during the last 5 years. In this study, we presented analytical data of flualprazolam to assist forensic laboratories that encounter these newly emerging compounds in casework. This is the first report on this compound in illegal products.

Funder

Fundamental Research Fund of the Institute of Forensic Science of the Ministry of Public Security

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry, medical,Toxicology,Pathology and Forensic Medicine

Reference12 articles.

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2. United Nations Office on Drugs and Crime (UNODC) (2013) The challenge of new psychoactive substances. https://www.unodc.org/documents/scientific/NPS_2013_SMART.pdf . Accessed Mar 2013

3. Manchester KR, Lomas EC, Waters L, Dempsey FC, Maskell PD (2018) The emergence of new psychoactive substance (NPS) benzodiazepines: a review. Drug Test Anal 10:37–53. https://doi.org/10.1002/dta.2211

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