Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B

Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B–cell response

Published:2005-03-21 Issue:8 Volume:252 Page:968-971
ISSN:0340-5354
Container-title:Journal of Neurology
language:en
Short-container-title:J Neurol

Author:

Derfuss T.,Hohlfeld R.,Meinl E.

Publisher

Springer Science and Business Media LLC

Subject

Clinical Neurology,Neurology

Link

http://link.springer.com/content/pdf/10.1007/s00415-005-0794-z.pdf

Reference16 articles.

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2. Alvarez-Lafuente R, De Las Heras V, Bartolome M, Picazo JJ, Arroyo R (2004) Relapsing-remitting multiple sclerosis and human herpesvirus 6 active infection. Arch Neurol 61:1523–1527

3. Berti R, Brennan MB, Soldan SS, Ohayon JM, Casareto L, McFarland HF, et al. (2002) Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression. J Neurovirol 8:250–256

4. Challoner PB, Smith KT, Parker JD, MacLeod DL, Coulter SN, Rose TM, et al. (1995) Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci 92:7440–7444

5. Chapenko S, Millers A, Nora Z, Logina I, Kukaine R, Murovsk M (2003) Correlation between HHV-6 reactivation and multiple sclerosis disease activity. J Med Virol 69:111–117

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