Shikonin inhibits TNF-α production through suppressing PKC-NF-κB-dependent decrease of IL-10 in rheumatoid arthritis-like cell model-Reference-Cited by-同舟云学术

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Shikonin inhibits TNF-α production through suppressing PKC-NF-κB-dependent decrease of IL-10 in rheumatoid arthritis-like cell model

Published:2016-12-09 Issue:2 Volume:71 Page:349-356
ISSN:1340-3443
Container-title:Journal of Natural Medicines
language:en
Short-container-title:J Nat Med

Author:

Sun Wen-Xiao,Liu Yan,Zhou Wei,Li He-Wei,Yang Jian,Chen Zhen-Bing

Funder

Science and Technology Planning Natural Scientific Foundation of Hubei Province of China

Publisher

Springer Science and Business Media LLC

Subject

Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s11418-016-1064-3.pdf

Reference47 articles.

1. Filippin LI, Vercelino R, Marroni N, Xavier RM (2008) Redox signalling and the inflammatory response in rheumatoid arthritis. Clin Exp Immunol 152:415–422

2. Cheon H, Yu SJ, Yoo D, Chae I, Song G, Sohn J (2002) Increased expression of pro-inflammatory cytokines and metalloproteinase-1 by TGF-β1 in synovial fibroblasts from rheumatoid arthritis and normal individuals. Clin Exp Immunol 127:547–552

3. Xu H, He Y, Yang X, Liang L, Zhan Z, Ye Y, Sun L (2007) Anti-malarial agent artesunate inhibits TNF-α-induced production of proinflammatory cytokines via inhibition of NF-κB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. Rheumatology 46:920–926

4. Bartok B, Firestein GS (2010) Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol Rev 233:233–255

5. Kawashima M, Ogura N, Akutsu M, Ito K, Kondoh T (2013) The anti-inflammatory effect of cyclooxygenase inhibitors in fibroblast-like synoviocytes from the human temporomandibular joint results from the suppression of PGE2 production. J Oral Pathol Med 42:499–506

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1. Omics-based pharmacological evaluation reveals Yuanhu Zhitong oral liquid ameliorates arthritis by regulating PKC/ERK/NF-κB signaling pathway;Journal of Ethnopharmacology;2024-09

2. Rheumatoid arthritis—recent advances in pathogenesis and the anti-inflammatory effect of plant-derived COX inhibitors;Naunyn-Schmiedeberg's Archives of Pharmacology;2024-02-15

3. Recent advances in shikonin for the treatment of immune-related diseases: Anti-inflammatory and immunomodulatory mechanisms;Biomedicine & Pharmacotherapy;2023-09

4. Topical Formulation Based on Arnebia euchroma as a Novel Possible Efficient Treatment on Epidermolysis Bullosa Lesions: A Case Series of Fourteen Patients;South East European Journal of Immunology;2023-07-20

5. Therapeutic effects of shikonin on adjuvant-induced arthritis in rats and cellular inflammation, migration and invasion of rheumatoid fibroblast-like synoviocytes via blocking the activation of Wnt/β-catenin pathway;Phytomedicine;2023-07

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