Sinomenine and magnoflorine, major constituents of Sinomeni Caulis et Rhizoma, show potent protective effects against membrane damage induced by lysophosphatidylcholine in rat erythrocytes

Author:

Sakumoto Hitoshi,Yokota Yumiko,Ishibashi Gakushi,Maeda Shouta,Hoshi Chihiro,Takano Haruyo,Kobayashi Miki,Yahagi Tadahiro,Ijiri Soichiro,Sakakibara Iwao,Hara Akiyoshi

Publisher

Springer Science and Business Media LLC

Subject

Molecular Medicine

Reference27 articles.

1. Das DK, Engelman RM, Rousou JA, Breyer RH, Otani H, Lemeshow S (1986) Role of membrane phospholipids in myocardial injury induced by ischemia and reperfusion. Am J Physiol 251:H71–H79

2. Mock T, Man RY (1990) Mechanism of lysophosphatidylcholine accumulation in the ischemic canine heart. Lipids 25:357–362

3. Hashizume H, Hoque AN, Magishi K, Hara A, Abiko Y (1997) A new approach to the development of anti-ischemic drugs. Substances that counteract the deleterious effect of lysophosphatidylcholine on the heart. Jpn Heart J 38:11–25

4. Corr PB, Saffitz JE, Sobel BE (1987) Lysophospholipids, long chain acylcarnitines and membrane dysfunction in the ischaemic heart. Basic Res Cardiol 82(Suppl 1):199–208

5. DaTorre SD, Creer MH, Pogwizd SM, Corr PB (1991) Amphipathic lipid metabolites and their relation to arrhythmogenesis in the ischemic heart. J Mol Cell Cardiol 23(Suppl 1):11–22

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