Ephedrine alkaloids-free Ephedra Herb extract: a safer alternative to ephedra with comparable analgesic, anticancer, and anti-influenza activities

Author:

Hyuga Sumiko,Hyuga Masashi,Oshima Naohiro,Maruyama Takuro,Kamakura Hiroyuki,Yamashita Tadatoshi,Yoshimura Morio,Amakura Yoshiaki,Hakamatsuka Takashi,Odaguchi Hiroshi,Goda Yukihiro,Hanawa Toshihiko

Funder

the Research on Development of New Drugs from Japan Agency for Medical Research and Development, AMED

a Grant-in-Aid from the Japan Health Sciences Foundation (Public-private sector joint research on Publicly Essential Drugs).

Publisher

Springer Science and Business Media LLC

Subject

Molecular Medicine

Reference24 articles.

1. The Ministry of Health, Labour, and Welfare of Japan (2011)  The Japanese Pharmacopoeia, 16th edn. Tokyo, Japan

2. Hikino H, Konno C, Takata H, Tamada M (1980) Antiinflammatory principle of Ephedra Herbs. Chem Pharm Bull (Tokyo) 28:2900–2904

3. Mantani N, Andoh T, Kawamata H, Terasawa K, Ochiai H (1999) Inhibitory effect of Ephedrae herba, an oriental traditional medicine, on the growth of influenza A/PR/8 virus in MDCK cells. Antivir Res 44:193–200

4. Hyuga S, Shiraishi M, Hyuga M, Goda Y, Hanawa T (2011) Ephedrae herba, a major component of maoto, inhibits the HGF-induced motility of human breast cancer MDA-MB-231 cells though suppression of c-Met tyrosine phosphorylation and c-Met expression. J Trad Med 28:128–138

5. Ling AM (2004) FDA to ban sales of dietary supplements containing ephedra. J Law Med Ethics 32:184–186

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