Betulinic acid attenuates liver fibrosis by inducing autophagy via the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway-Reference-Cited by-同舟云学术

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Betulinic acid attenuates liver fibrosis by inducing autophagy via the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway

Published:2018-10-30 Issue:1 Volume:73 Page:179-189
ISSN:1340-3443
Container-title:Journal of Natural Medicines
language:en
Short-container-title:J Nat Med

Author:

Liu Yuan,Bi Yanmeng,Mo Chan,Zeng Ting,Huang Sha,Gao Lei,Sun Xuegang,Lv Zhiping^ORCID

Funder

National Natural Science Foundation of China

Guangdong Science and Technology Department

Administration of Traditional Chinese Medicine of Guangdong Province

Science and Technology Planning Project of Guangzhou City

the Scientific Research Initiative Program of Southern Medical University

the Natural Science Foundation of Guangdong Province

Publisher

Springer Science and Business Media LLC

Subject

Molecular Medicine

Link

http://link.springer.com/article/10.1007/s11418-018-1262-2/fulltext.html

Reference42 articles.

1. Schuppan D, Pinzani M (2012) Anti-fibrotic therapy: lost in translation? J Hepatol 56(Suppl 1):S66–S74. https://doi.org/10.1016/S0168-8278(12)60008-7

2. Kubow KE, Vukmirovic R, Zhe L, Klotzsch E, Smith ML, Gourdon D, Luna S, Vogel V (2015) Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix. Nat Commun 6:8026. https://doi.org/10.1038/ncomms9026

3. Zou X, Ramachandran P, Kendall TJ, Pellicoro A, Dora E, Aucott RL, Manwani K, Man TY, Chapman KE, Henderson NC, Forbes SJ, Webster SP, Iredale JP, Walker BR, Michailidou Z (2018) 11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis. Hepatology (Baltimore, Md.) 67:2167–2181. https://doi.org/10.1002/hep.29734

4. Fujioka T, Kashiwada Y, Kilkuskie RE, Cosentino LM, Ballas LM, Jiang JB, Janzen WP, Chen IS, Lee KH (1994) Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzygium claviflorum, and the anti-HIV activity of structurally related triterpenoids. J Nat Prod 57:243–247

5. Damle AA, Pawar YP, Narkar AA (2013) Anticancer activity of betulinic acid on MCF-7 tumors in nude mice. Indian J Exp Biol 51:485–491

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