Methotrexate induces germ cell apoptosis and impairs spermatogenesis in a rat

Author:

Sukhotnik Igor,Nativ Omri,Roitburt Alex,Bejar Daniel,Coran Arnold G.,Mogilner Jorge G.,Nativ Ofer

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Surgery,Pediatrics, Perinatology and Child Health

Reference22 articles.

1. Bleyer WA (1977) Methotrexate: clinical pharmacology, current status and therapeutic guidelines. Cancer Treat Rev 4:87–101

2. Freeman-Narrod M (1962) The pharmacology of methotrexate. In: Porte R, Wiltshaw E (eds) Methotrexate in the treatment of cancer. The Williams & Wilkins Co, Battimore, pp 17–21

3. Goldman ID, Matherly LH (1985) The cellular pharmacology of methotrexate. Pharmacol Ther 28:77–102

4. Chu E, Allegra CJ (1996) Antifolates. In: Chabner BA, Longo DL (eds) Cancer chemotherapy and biotherapy principles and practice. Lippincott-Raver, Philadelphia, pp 109–148

5. Kerr JF, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide- ranging implications in tissue kinetics. Br J Cancer 26:239–257

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