Guided de-escalation of DAPT in acute coronary syndrome patients undergoing percutaneous coronary intervention with BVS implantation: a post-hoc analysis from the randomized TROPICAL-ACS trial

Author:

Koltowski LukaszORCID,Tomaniak Mariusz,Gross Lisa,Rymuza Bartosz,Kowara Michal,Parma Radoslaw,Komosa Anna,Klopotowski Mariusz,Jacobshagen Claudius,Gori Tommaso,Aradi Daniel,Huber Kurt,Hadamitzky Martin,Massberg Steffen,Lesiak Maciej,Filipiak Krzysztof J.,Witkowski Adam,Opolski Grzegorz,Huczek Zenon,Sibbing Dirk

Funder

Klinikum der Universität München

Roche

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Hematology

Reference25 articles.

1. Sibbing D, Aradi D, Jacobshagen C et al (2016) A randomised trial on platelet function-guided de-escalation of antiplatelet treatment in ACS patients undergoing PCI. Thromb Haemost 117:188–195. https://doi.org/10.1160/TH16-07-0557

2. Sibbing D, Aradi D, Jacobshagen C et al (2017) Guided de-escalation of antiplatelet treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention (TROPICAL-ACS): a randomised, open-label, multicentre trial. Lancet 390:1747–1757. https://doi.org/10.1016/S0140-6736(17)32155-4

3. Sibbing D, Gross L, Rieber J et al (2018) Age and outcomes following guided de-escalation of antiplatelet treatment in acute coronary syndrome patients undergoing percutaneous coronary intervention: results from the randomized TROPICAL-ACS trial. Eur Heart J. https://doi.org/10.1093/eurheartj/ehy332

4. Antman EM, Wiviott SD, Murphy SA et al (2008) Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel-Thrombolysis In Myocardial Infarction) analysis. J Am Coll Cardiol 51:2028–2033. https://doi.org/10.1016/j.jacc.2008.04.002

5. Becker RC, Bassand J-P, Budaj A et al (2011) Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial. Eur Heart J 32:2933–2944. https://doi.org/10.1093/eurheartj/ehr422

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