New oral anticoagulants

Author:

Galanis Taki,Thomson Lynda,Palladino Michael,Merli Geno J.

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Hematology

Reference42 articles.

1. Raghavan N, Frost CE, Yu Z et al (2009) Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos 37:74–81

2. Jiang X, Crain EJ, Luettgen JM et al (2009) Apixaban, an oral direct factor Xa inhibitor, inhibitis human clot-bound factor Xa activity in vitro. Thromb Haemost 101:780–782

3. Luettgen JM, Wang Z, Seiffer DA, et al (2007) Inhibition of measured thrombin generation in human plasma by Apixaban: a predictive mathematical model based on experimentally determined rate constants. J Thromb Haemost 5(Suppl 2):p-T-633

4. Frost C, Yu Z, Moore K, et al (2007) Apixaban, an oral direct factor Xa inhibitor: multiple-dose safety, pharmacokinetics and pharmacodynamics in healthy subjects. J Thromb Haemost 5:P-M-664

5. Kubitza D, Becka M, Wensing G et al (2005) Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939: an oral, direct Factor Xa inhibitor after multiple dosing in healthy male subjects. Eur J Clin Pharmacol 61:873–880

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