Juvenile patients with the homozygous MTHFR C677T genotype develop ischemic stroke 5 years earlier than wild type
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine,Hematology
Link
https://link.springer.com/content/pdf/10.1007/s11239-022-02678-6.pdf
Reference46 articles.
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2. Binia A, Contreras AV, Canizales-Quinteros S et al (2014) Geographical and ethnic distribution of single nucleotide polymorphisms within genes of the folate/homocysteine pathway metabolism. Genes Nutr 9:421
3. Cui T (2016) MTHFR C677T mutation increased the risk of Ischemic Stroke, especially in large-artery atherosclerosis in adults: an updated meta-analysis from 38 researches. Int J Neurosci 126:10–19
4. Sarecka-Hujar B, Kopyta I, Pienczk-Reclawowicz K et al (2012) The TT genotype of methylenetetrahydrofolate reductase 677C>T polymorphism increases the susceptibility to pediatric ischemic stroke: meta-analysis of the 822 cases and 1,552 controls. Mol Biol Rep 39:7957–7963
5. Kumar A, Kumar P, Prasad M et al (2015) Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR gene) with ischemic stroke: a meta-analysis. Neurol Res 37:568–577
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