On-treatment platelet reactivity through the thromboxane A2 or P2Y12 platelet receptor pathways is not affected by pelacarsen
Author:
Funder
Ionis Pharmaceuticals
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine,Hematology
Link
https://link.springer.com/content/pdf/10.1007/s11239-023-02818-6.pdf
Reference34 articles.
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2. Tsimikas S, Moriarty PM, Stroes ES (2021) Emerging RNA therapeutics to lower blood levels of lp(a): JACC Focus Seminar 2/4. J Am Coll Cardiol 77:1576–1589
3. Tsimikas S, Karwatowska-Prokopczuk E, Gouni-Berthold I et al (2020) Lipoprotein(a) reduction in persons with cardiovascular disease. N Engl J Med 382:244–255
4. O’Donoghue ML, Rosenson RS, Gencer B et al (2022) Small interfering RNA to reduce lipoprotein(a) in Cardiovascular Disease. N Engl J Med 387:1855–1864
5. Nissen SE, Wolski K, Balog C et al (2022) Single ascending dose study of a short interfering RNA targeting lipoprotein(a) production in individuals with elevated plasma lipoprotein(a) levels. JAMA 327:1679–1687
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