Effect on ex vivo platelet aggregation and in vivo cyclic flow with Na+/H+ exchange inhibition

Author:

Gumina Richard J.,Newman Peter J.,Gross Garrett J.

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Hematology

Reference27 articles.

1. Borin ML, Pinelis VG, Azizova OA, Kudinov YV, Markov CM, Cragoe EJ, Khodorov BI (1989) Na+/H+ exchange in PAF-stimulated platelets. J Lipid Mediat 1(5):257–272

2. Connolly TM, Limbird LE (1983) Removal of extraplatelet Na+ eliminates indomethacin-sensitive secretion from human platelets stimulated by epinephrine, ADP, and thrombin. Proc Natl Acad Sci USA 80(17):5320–5324

3. Gumina RJ, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ (1999) Inhibition of the Na(+)/H(+) exchanger confers greater cardioprotection against 90 min of myocardial ischemia than ischemic preconditioning in dogs. Circulation 100(25):2519–2526; discussion 2469–2572

4. Gumina RJ, Mizumura T, Beier N, Schelling P, Schultz JJ, Gross GJ (1998) A new sodium/hydrogen exchange inhibitor, EMD 85131, limits infarct size in dogs when administered before or after coronary artery occlusion. J Pharmacol Exp Ther 286(1):175–183

5. Gumina RJ, Auchampach J, Wang R, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ (2000) Na(+)/H(+) exchange inhibition-induced cardioprotection in dogs: effects on neutrophils versus cardiomyocytes. Am J Physiol Heart Circ Physiol 279(4):H1563–H1570

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