The ratio of concentrations of aminocaproic acid and tranexamic acid that prevent plasmin activation of platelets does not provide equivalent inhibition of plasmatic fibrinolysis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine,Hematology
Link
http://link.springer.com/article/10.1007/s11239-018-1705-3/fulltext.html
Reference15 articles.
1. Gerstein NS, Brierley JK, Windsor J, Panikkath PV, Ram H, Gelfenbeyn KM, Jinkins LJ, Nguyen LC, Gerstein WH (2017) Antifibrinolytic agents in cardiac and noncardiac surgery: a comprehensive overview and update. J Cardiothorac Vasc Anesth 31:2183–2205
2. Alkjaersig N, Fletcher AP, Sherry S (1959) ε-Aminocaproic acid: an inhibitor of plasminogen activation. J Biol Chem 234:832–837
3. Iwamoto M (1975) Plasminogen-plasmin system IX. Specific binding of tranexamic acid to plasmin. Thromb Diath Haemorrh 33:573–585
4. Lu H, Soria C, Li H, Soria J, Lijnen HR, Perrot JY, Caen JP (1991) Role of active center and lysine binding sites of plasmin in plasmin-induced platelet activation and disaggregation. Thromb Haemost 65:67–72
5. Soslau G, Horrow J, Brodsky I (1991) Effect of tranexamic acid on platelet ADP during extracorporeal circulation. Am J Hematol 38:113–119
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