A double-blind placebo controlled trial with oral ambroxol and N-acetylcysteine for mucolytic treatment in cystic fibrosis

Author:

Ratjen F.,W�nne R.,Posselt H.-G.,St�ver B.,Hofmann D.,Bender S. W.

Publisher

Springer Science and Business Media LLC

Subject

Pediatrics, Perinatology and Child Health

Reference27 articles.

1. Boman G, B�cker U, Larsson S, Melander B, Wahlander L (1983) Oral acetylcysteine reduces exacerbation rate in chronic bronchitis: report of a trial organized by the Swedish Society for Pulmonary Diseases. Eur J Respir Dis 64:405?415

2. Chrispin AR, Norman AP (1974) The systematic evaluation of the chest radiograph in cystic fibrosis. Pediatr Radiol 2:101?106

3. Denton R, Kwart H, Litt M (1967) N-acetylcysteine in cystic fibrosis. Am Rev Respir Dis 95:643?651

4. Du Bois AB, Botelho SY, Bedell GN, Marshall R, Comroe JH (1956) A rapid plethysmographic method for measuring thoracic gas volume: A comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects. J Clin Invest 35 I:322?326

5. Engstr�m I, Escard� FE, Karlberg P, Kraepelien S (1958) Respiratory studies in children. VI. Timed vital capacity in healthy children and in symptom free asthmatic children. Acta Paediatr 48:114?120

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