Missing Nuts and Bolts: Translating Pulmonary Fibrosis from Preclinical Murine Models to Human Clinical Trials
Author:
Funder
National Heart, Lung, and Blood Institute
National Institute of General Medical Sciences
University of Kansas Medical Center, School of Medicine, Internal Medicine Start-Up Funds
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00408-024-00676-4.pdf
Reference5 articles.
1. Chang A, Van Ry PM, Raghu G (2023) Idiopathic pulmonary fibrosis: aligning murine models to clinical trials in humans. Lancet Respir Med 11(11):953–955
2. Rodt T, von Falck C, Dettmer S et al (2010) Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-beta1. Respir Res 11(1):181
3. Devos FC, Maaske A, Robichaud A et al (2017) Forced expiration measurements in mouse models of obstructive and restrictive lung diseases. Respir Res 18(1):123
4. Tashiro J, Rubio GA, Limper AH et al (2017) Exploring animal models that resemble idiopathic pulmonary fibrosis. Front Med (Lausanne) 4:118
5. Ahangari F, Becker C, Foster DG et al (2022) Saracatinib, a selective Src kinase inhibitor, blocks fibrotic responses in preclinical models of pulmonary fibrosis. Am J Respir Crit Care Med 206(12):1463–1479
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