Current Challenges and Potential Strategies for Designing a New Generation of Chimeric Antigen Receptor-T cells with High Anti-tumor Activity in Solid Tumors
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s43152-023-00043-0.pdf
Reference99 articles.
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2. •• Karlsson H, Svensson E, Gigg C, Jarvius M, Olsson-Strömberg U, Savoldo B, Dotti G, Loskog A. Evaluation of intracellular signaling downstream chimeric antigen receptors. PLoS ONE. 2015; https://doi.org/10.1371/journal.pone.0144787. Review suggesting other signaling pathways be considered while designing the next-generation CAR.
3. Oluwole OO, Davila ML. At The Bedside: Clinical review of chimeric antigen receptor (CAR) T cell therapy for B cell malignancies. J Leukoc Biol. 2016;100:1265–72. https://doi.org/10.1189/jlb.5bt1115-524r.
4. •• Zabel M, Tauber PA, Pickl WF. The making and function of CAR cells. Immunol Lett. 2019; https://doi.org/10.1016/j.imlet.2019.06.002. It gives detailed information about the construction and function of CAR cells.
5. Bao F, Wan W, He T, Qi F, Liu G, Hu K, Lu XA, Yang P, Dong F, Wang J, Jing H. Autologous CD19-directed chimeric antigen receptor-T cell is an effective and safe treatment to refractory or relapsed diffuse large B-cell lymphoma. Cancer Gene Ther. 2019;26:248–55. https://doi.org/10.1038/s41417-018-0073-7.
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