Increased methotrexate-induced chromosome breakage in patients with free trisomy 21 and their parents

Author:

Pelz Lothar,G�tz J�rgen,Kr�ger Gabriele,Witt Gabriele

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics

Reference18 articles.

1. Aldenhoff P, Wegner RD, Sperling K (1980) Different sensitivity of diploid and trisomic cells from patients with Down syndrome mosaic after treatment with the trifunctional alkylating agent trenimon. Hum Genet 56:123?125

2. Alfi OS, Chang R, Azen SP (1980) Evidence for genetic control of nondisjunction in man. Am J Hum Genet 32:477?483

3. Crowley PH, Gulati DK, Hayden TL, Lopez P, Dyer R (1979) A chiasma-hormonal hypothesis relating Down's syndrome and maternal age. Nature 280:417?418

4. Hamers AJ, Jongbloet PH, Poestkoke AJ (1981) Parental origin of the extra chromosome 21 in Down's syndrome. In: Burgio GR, Fraccaro M, Tiepolo L, Wolf U (eds) Trisomy 21. International Symposium Convento delle Clarisse, Rapallo 1979. Springer, Berlin Heidelberg New York, p 242 (abstr)

5. ISCN (1978) An international system for human cytogenetic nomenclature. Cytogenet Cell Genet 21:363?371

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