Intrauterine Drug Exposure—What the Pediatrician Needs to Know. Part 1: General Overview, Transplacental Drug Transfer, Teratogenicity, and Fetal Alcohol Spectrum Disorder

Author:

Cortez Josef,Hudak Mark L.

Publisher

Springer Science and Business Media LLC

Subject

Pediatrics, Perinatology and Child Health

Reference94 articles.

1. Williams JF, Smith VC. Fetal alcohol spectrum disorders. Pediatrics. 2015;136:e1395–406. This paper presents a comprehensive review of the range of manifestations, diagnosis, neurocognitive and behavioral outcomes, and multidisciplinary approach to FASD. This article also discusses advocacy and public policy implementation to assist children, their families, and the community to address FASD and to curb alcohol consumption during pregnancy.

2. Patrick SW, Barfield WD, Poindexter BB, Committee On Fetus and Newborn, Committee on Substance Abuse and Prevention. Neonatal opioid withdrawal syndrome. Pediatrics. 2020;146. This clinical report provides an overview of the effect of the opioid crisis on the mother-infant dyad as well as recommendations for management of the infant with opioid exposure, including clinical presentation, assessment, treatment, and discharge.

3. Hudak ML, Tan RC, Committee On Drugs, Committee On Fetus and Newborn American Academy of Pediatrics. Neonatal drug withdrawal. Pediatrics. 2012;129:e540–60. This clinical guideline set the stage for quality improvement efforts with respect to improving outcomes of newborns with NAS and emphasized that non-pharmacologic care was the essential first element of treatment. This paper also contains guidance on how to wean infants from iatrogenic withdrawal syndromes due to in-hospital use of opioids and benzodiazepines.

4. Kocherlakota P. Neonatal abstinence syndrome. Pediatrics. 2014;134:e547–61.

5. McQueen K, Murphy-Oikonen J. Neonatal abstinence syndrome. N Engl J Med. 2016;375:2468–79.

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