Cellular restriction factors affecting the early stages of HIV replication
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Virology
Link
http://link.springer.com/content/pdf/10.1007/s11904-006-0004-3.pdf
Reference63 articles.
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3. Zheng YH, Lovsin N, Peterlin BM: Newly identified host factors modulate HIV replication. Immunol Lett 2005, 97:225–234.
4. Sheehy AM, Gaddis NC, Choi JD, Malim MH: Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 2002, 418:646–650. This is a landmark paper identifying a cellular protein (CEM15) that obstructs HIV replication in restrictive cells without Vif. This study implies Vif improves virion infectivity by overcoming the antiviral activity of CEM15.
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