HIV-1 Prevention for HIV-1 Serodiscordant Couples

Author:

Curran Kathryn,Baeten Jared M.,Coates Thomas J.,Kurth Ann,Mugo Nelly R.,Celum Connie

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Virology

Reference104 articles.

1. UNAIDS: Global Report: UNAIDS Report on the Global AIDS Epidemic. 2010. Available at http://www.unaids.org/globalreport/Global_report.htm . Accessed December 14, 2011.

2. •• Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493–505. This is the first randomized clinical trial to demonstrate that early initiation of ART (between CD4 350–550 cells/mL) significantly reduces the likelihood of transmitting HIV-1 to sexual partners. HIV-1 serodiscordant couples initiating ART early had 96% fewer HIV-1 infections and had lower incidence of tuberculosis..

3. •• Baeten J, Donnell D Ndase P, Mugo N, Mujugira A, Celum C, et al. Antiretroviral pre-exposure prophylaxis for HIV-1 prevention among heterosexual men and women. CROI 2012, abstract 29. This randomized clinical trial demonstrated high efficacy of daily oral PrEP in preventing HIV-1 transmission in HIV-1 serodiscordant couples in sub-Saharan Africa: 67% with tenofovir and 75% with emtricitabine/tenofovir.

4. Anand A, Shiraishi RW, Bunnell RE, et al. Knowledge of HIV status, sexual risk behaviors and contraceptive need among people living with HIV in Kenya and Malawi. AIDS. 2009;23(12):1565–73.

5. De Walque D. Sero-discordant couples in five African countries: implications for prevention strategies. Popul Dev Rev. 2007;33(3):501–23.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3