Understanding HIV Compartments and Reservoirs-Reference-Cited by-同舟云学术

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Understanding HIV Compartments and Reservoirs

Published:2014-04-15 Issue:2 Volume:11 Page:186-194
ISSN:1548-3568
Container-title:Current HIV/AIDS Reports
language:en
Short-container-title:Curr HIV/AIDS Rep

Author:

Svicher Valentina,Ceccherini-Silberstein Francesca,Antinori Andrea,Aquaro Stefano,Perno Carlo Federico

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Virology

Link

http://link.springer.com/content/pdf/10.1007/s11904-014-0207-y.pdf

Reference94 articles.

1. Eisele E, Siliciano RF. Redefining the viral reservoirs that prevent HIV-1 eradication. Immunity. 2012;37:377–88. This perspective proposes definitions for key terms in the field of HIV-1 latency, reservoirs and eradication. This paper represents a starting point for refining the terminology in cure research.

2. Hocqueloux L, Avettand-Fènoël V, Jacquot S, et al. Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts. J Antimicrob Chemother. 2013;68:1169–78.

3. Sáez-Cirión A, Bacchus C, Hocqueloux L, et al. Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study. PLoS Pathog. 2013;9:e1003211. This paper showed that early and prolonged antiretroviral treatment can reduce the burden of HIV-1 cellular reservoirs in some patients including those with an unfavorable genetic profile in controlling HIV infection. This paper highlights that an early treatment may represent a strategy aimed at achieving functional HIV cure.

4. Finzi D, Blankson J, Siliciano JD, et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med. 1999;5:512–7.

5. Chomont N, El-Far M, Ancuta P, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med. 2009;15:893–900.

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