Preliminary pharmacological and clinical results with desmethylimipramine (DMI) G 35020, a metabolite of imipramine

Author:

Brodie B.,Dick P.,Kielholz P.,P�ldinger W.,Theobald W.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference13 articles.

1. Brodie, B. B., M. Bickel and F. Sulser: Desmethylimipramine, a new type of antidepressant drug. (In press.)

2. Domenjoz, R., and W. Theobald: Zur Pharmakologie des Tofranil (N-(3-Dimethylaminopropyl)-iminodibenzyl-hydrochlorid). Arch. int. Pharmacodyn. 120, 450?489 (1959).

3. Gillette, J. R., J. V. Dingell, F. Sulser, R. Kuntzman and B. B. Brodie: Isolation from rat brain of a metabolic product, desmethylimipramine, that mediates the antidepressant activity of imipramine (Tofranil). Experientia (Basel) 17, 417?418 (1961).

4. Grünthal, E.: Unpublished reports (submitted May 14, 1960).

5. Herrmann, B., and R. Pulver: Der Stoffwechsel des Psychopharmakons Tofranil. Arch. int. Pharmacodyn. 126, 454?469 (1960).

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