De novo systemic atypical hemolytic uremic syndrome in an ABO-incompatible living kidney transplant recipient with a novel pathogenic CFHR1 gene mutation successfully treated with eculizumab: a case report-Reference-Cited by-同舟云学术

De novo systemic atypical hemolytic uremic syndrome in an ABO-incompatible living kidney transplant recipient with a novel pathogenic CFHR1 gene mutation successfully treated with eculizumab: a case report

Published:2022-07-19 Issue:7 Volume:35 Page:1895-1899
ISSN:1724-6059
Container-title:Journal of Nephrology
language:en
Short-container-title:J Nephrol

Author:

Li Dawei,Wang Wei,Chen Ruoyang,Wen Jiqiu,Zhang Ming

Funder

National Natural Science Foundation of China

Special Supportive Program for Organ Transplantation

Publisher

Springer Science and Business Media LLC

Subject

Nephrology

Link

https://link.springer.com/content/pdf/10.1007/s40620-022-01391-0.pdf

Reference13 articles.

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4. Heinen S, Hartmann A, Lauer N, Wiehl U, Dahse HM, Schirmer S, Gropp K, Enghardt T, Wallich R, Hälbich S, Mihlan M, Schlötzer-Schrehardt U, Zipfel PF, Skerka C (2009) Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation. Blood 114(12):2439–2447

5. Bhattacharjee A, Reuter S, Trojnár E, Kolodziejczyk R, Seeberger H, Hyvärinen S, Uzonyi B, Szilágyi Á, Prohászka Z, Goldman A, Józsi M, Jokiranta TS (2015) The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease. J Biol Chem 290(15):9500–9510