pcDNA3.1(−)-mediated ribozyme targeting of HER-2 suppresses breast cancer tumor growth

Author:

He Pei,Zhu Dan,Hu Jun-Jian,Peng Ju,Chen Lian-Sheng,Lu Guang-Xiu

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,General Medicine

Reference33 articles.

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2. Yarden Y, Sliwkowski MX (2001) Untangling the ErbB signaling network. Nat Rev Mol Cell Biol 2:127–137

3. Press MF, Cordon-Cardo C, Slamon D (1990) Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues. Oncogene 5:953–962

4. Bargmann CI, Hung MC, Weinberg RA (1986) Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell 45:649–657

5. Slamon DJ, Clark GM, Wong SG et al (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235:177–182

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