Intra-tracheal delivery of mesenchymal stem cell-conditioned medium ameliorates pathological changes by inhibiting apoptosis in asthmatic rats-Reference-Cited by-同舟云学术

Intra-tracheal delivery of mesenchymal stem cell-conditioned medium ameliorates pathological changes by inhibiting apoptosis in asthmatic rats

Published:2022-02-03 Issue:5 Volume:49 Page:3721-3728
ISSN:0301-4851
Container-title:Molecular Biology Reports
language:en
Short-container-title:Mol Biol Rep

Author:

Keyhanmanesh Rana,Khodamoradi Fatemeh,Rahbarghazi Reza,Rahbarghazi Afshin,Rezaie Jafar,Ahmadi Mahdi^ORCID,Salimi Leila,Delkhosh Aref

Funder

University of Tabriz

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s11033-022-07212-8.pdf

Reference29 articles.

1. Ahmadi M, Rahbarghazi R, Shahbazfar A-A, Baghban H, Keyhanmanesh R (2018) Bone marrow mesenchymal stem cells modified pathological changes and immunological responses in ovalbumin-induced asthmatic rats possibly by the modulation of miRNA155 and miRNA133. Gen Physiol Biophys 37(3):263–274

2. Afzal S, Ramzan K, Waqar AB (2020) Alternative approaches for the treatment of asthma and COPD: focus on cell-based therapies, epigenetics, and gene silencing approaches. Adv Life Sci 7(3):181–189

3. Rahbarghazi R, Keyhanmanesh R, Aslani MR, Hassanpour M, Ahmadi M (2019) Bone marrow mesenchymal stem cells and condition media diminish inflammatory adhesion molecules of pulmonary endothelial cells in an ovalbumin-induced asthmatic rat model. Microvasc Res 121:63–70

4. Keyhanmanesh R, Rahbarghazi R, Aslani MR, Hassanpour M, Ahmadi M (2018) Systemic delivery of mesenchymal stem cells condition media in repeated doses acts as magic bullets in restoring IFN-γ/IL-4 balance in asthmatic rats. Life Sci 212:30–36

5. Mirershadi F, Ahmadi M, Rezabakhsh A, Rajabi H, Rahbarghazi R, Keyhanmanesh R (2020) Unraveling the therapeutic effects of mesenchymal stem cells in asthma. Stem Cell Res Ther 11(1):1–12

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