The importance of choice of agonist in studies designed to predict ? 2:? 1 adrenoceptor selectivity of antagonists from pA2 values on guinea-pig trachea and atria

Author:

O'Donnell Stella R.,Wanstall Janet C.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Reference31 articles.

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2. Barrett, A. M.: The pharmacology of atenolol. Postgrad. Med. J. 53, (Suppl. 3), 58?64 (1977)

3. Broadley, K. J., Lumley, P.: Selective reserpine-induced supersensitivity of the positive inotropic and chronotropic responses to isoprenaline and salbutamol in guinea-pig isolated atria. Br. J. Pharmacol. 59, 51?60 (1977)

4. Buckner, C. K., Saini, R. K.: On the use of functional antagonism to estimate dissociation constants for Beta adrenergic receptor agonists in isolated guinea-pig trachea. J. Pharmacol. Exp. Ther. 194, 565?574 (1975)

5. Carlsson, E., �blad, B.: Are there two types of beta-receptors mediating the same adrenergic response. In: Beta-adrenoceptor blocking agents (P. R. Saxena and R. P. Forsyth, eds.), pp. 305?309. Amsterdam: North-Holland Publishing Company 1976

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