Simple model to explain effects of plasma protein binding and tissue binding on calculated volumes of distribution, apparent elimination rate constants and clearances
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00563079.pdf
Reference18 articles.
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2. Anton, A.H., Solomon, H.M.: Drug-protein binding. Ann. N. Y. Acad. Sci.226, 1?362 (1973)
3. Benya, T.J., Wagner, J.G.: Rapid equilibration of warfarin between rat tissue and plasma. J. Pharmacokin. Biopharm.3, 237?255 (1975)
4. Bischoff, K.B., Dedrick, R.L.: Thiopental pharmacokinetics. J. pharm. Sci.57, 1346?1351 (1968)
5. Coffey, J.J.: Effects of protein binding of drugs on areas under plasma concentration-time curves. J. pharm. Sci.61, 138?139 (1972)
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