Development of Magnetic Solid Phase Micro-Extraction (MSPE) Method for the Extraction and Preconcentration of the Selected β-Blockers in the Environmental Wastewaters

Author:

Waleng Ngwako Joseas,Selahle Shirley Kholofelo,Mpupa Anele,Zhang Yongjun,Nomngongo Philiswa NosizoORCID

Abstract

AbstractEmerging organic pollutants s have always been the greatest environmental concern due to their ubiquity and distinguished adverse effects. These are mostly water-bone pollutants flagged as endocrine disruptors and can greatly inconvenience the ecosystem. Among others, β-blockers have also been detected in the environment at various concentrations that threaten the well-being of humans and animals. In this work, NH2-MIL-101(Cr) doped magnetic nanoparticles nanocomposite was successfully synthesised and characterised using analytical techniques such as X-ray diffraction spectroscopy (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), Brunauer-Emmett-Teller (BET) and transmission electron microscopy (TEM). The Fe3O4@NH2-MIL-101(Cr) was then used as an adsorbent to extract the selected β-blockers in the environmental wastewater. The selected β-blockers were quantified using a high-performance liquid chromatography-diode array detector (HPLC-DAD). Parameters affecting the extraction were screened and optimised using fractional factorial design (FFD) and central composite design (CCD), respectively. Under optimum conditions, the LODs were 0.057 and 0.065 µg L− 1, and LOQs were 0.19 and 0.22 µg L− 1 for acebutolol (ACE) and metoprolol (MET), respectively. The calibration curve exhibited the linearity range of 0.2–1200 µg L− 1 with correlation coefficients of 0.9987 and 0.9968 for ACE and MET, respectively. Repeatability studies demonstrated the %RSD of 0.63 and 0.74% for MET and ACE. At the same time, reproducibility studies displayed the %RSD of 1.057 and 1.178% for MET and ACE, respectively. Spike recovery experiments were carried out to assess the performance of MSPE in real samples, and over 88% of both analytes were recovered. This indicated that the MSPE method could enrich various organic pollutants from different environmental matrices.

Funder

University of Johannesburg

Publisher

Springer Science and Business Media LLC

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3