Georg Schmorl prize of the German spine society (DWG) 2022: current treatment for inpatients with osteoporotic thoracolumbar fractures—results of the EOFTT study

Author:

Ullrich Bernhard W.ORCID,Schenk Philipp,Scheyerer Max J.,Bäumlein Martin,Katscher Sebastian,Schnake Klaus J.,Zimmermann Volker,Schwarz Falko,Schmeiser Gregor,Scherer Michael,Müller Michael,Sprengel Kai,Osterhoff Georg,Liepold Katja,Schramm Simon,Baron Christopher,Siekmann Holger,Franck Alexander,Isik N.,Klauke Friederike,Spiegl Ulrich J. A.,

Abstract

Abstract Aim Osteoporotic thoracolumbar fractures are of increasing importance. To identify the optimal treatment strategy this multicentre prospective cohort study was performed. Purpose Patients suffering from osteoporotic thoracolumbar fractures were included. Excluded were tumour diseases, infections and limb fractures. Age, sex, trauma mechanism, OF classification, OF-score, treatment strategy, pain condition and mobilization were analysed. Methods A total of 518 patients’ aged 75 ± 10 (41–97) years were included in 17 centre. A total of 174 patients were treated conservatively, and 344 were treated surgically, of whom 310 (90%) received minimally invasive treatment. An increase in the OF classification was associated with an increase in both the likelihood of surgery and the surgical invasiveness. Results Five (3%) complications occurred during conservative treatment, and 46 (13%) occurred in the surgically treated patients. 4 surgical site infections and 2 mechanical failures requested revision surgery. At discharge pain improved significantly from a visual analogue scale score of 7.7 (surgical) and 6.0 (conservative) to a score of 4 in both groups (p < 0.001). Over the course of treatment, mobility improved significantly (p = 0.001), with a significantly stronger (p = 0.007) improvement in the surgically treated patients. Conclusion Fracture severity according to the OF classification is significantly correlated with higher surgery rates and higher invasiveness of surgery. The most commonly used surgical strategy was minimally invasive short-segmental hybrid stabilization followed by kyphoplasty/vertebroplasty. Despite the worse clinical conditions of the surgically treated patients both conservative and surgical treatment led to an improved pain situation and mobility during the inpatient stay to nearly the same level for both treatments.

Publisher

Springer Science and Business Media LLC

Subject

Orthopedics and Sports Medicine,Surgery

Reference31 articles.

1. Rupp M, Walter N, Pfeifer C, Lang S, Kerschbaum M, Krutsch W, Baumann F, Alt V (2021) The incidence of fractures among the adult population of Germany-an analysis from 2009 through 2019. Dtsch Arztebl Int 118(40):665–669

2. Zhai G, Li A, Liu B, Lv D, Zhang J, Sheng W, Yang G, Gao Y (2021) A meta-analysis of the secondary fractures for osteoporotic vertebral compression fractures after percutaneous vertebroplasty. Medicine 100(16):e25396

3. Spiegl U, Bork H, Grüninger S, Maus U, Osterhoff G, Pieroh P, Schnoor J, Heyde C, Schnake K (2021) Osteoporotic fractures of the thoracic and lumbar vertebra: diagnosis and conservative treatment-a systematic review. Dtsch Arztebl Int 118(40):670–677

4. Wu Y, Wang F, Zhou J-Q, Liu C-Y, Wu R-X (2014) Analysis of clinical effects of percutaneous vertebroplasty and percutaneous kyphoplasty in treating osteoporotic vertebral compression fracture. Zhongguo Gu Shang = China J Orthop Traumatol 27(5):385–389

5. Buchbinder R, Osborne RH, Ebeling PR, Wark JD, Mitchell P, Wriedt C, Graves S, Staples MP, Murphy B (2009) A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 361(6):557–568

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3