Time to reach steady state and prediction of steady-state concentrations for drugs obeying Michaelis-Menten elimination kinetics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics
Link
http://link.springer.com/content/pdf/10.1007/BF01312263.pdf
Reference18 articles.
1. L. M. Michaelis and M. L. Menten. Die Kinetik der Invertinwirkung. Biochem. Z.49:333–369 (1913).
2. F. Lundquist and H. Wolthers. The kinetics of alcohol elimination in man.Acta Pharmacol. Toxicol. 14:265–289 (1958).
3. J. G. Wagner. A modern view of pharmacokinetics.J. Pharmacokin. Blopharm. 1:363–401 (1973).
4. N. Gerber and J. G. Wagner. Explanation of dose-dependent decline of diphenylhydantoin plasma levels by fitting to the integrated form of the Michaelis-Menten equation.Res. Commun. Chem. Pathol. Pharmacol. 3:455–466 (1972).
5. A. Richens. A study of the pharmacokinetics of phenytoin (diphenylhydantoin) in epileptic patients, and the development of a nomogram for making dose increments.Epilepsia 16:627–646 (1975).
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