Modern day screening for Lynch syndrome in endometrial cancer: the KEM experience

Author:

Pauly NinaORCID,Baert Thaïs,Schmutzler Rita,du Bois Andreas,Schneider Stephanie,Rhiem Kerstin,Schömig-Markiefka Birgid,Siemanowski Janna,Heikaus Sebastian,Traut Alexander,Heitz Florian,Prader Sonia,Ehmann Sarah,Harter Philipp,Ataseven Beyhan

Publisher

Springer Science and Business Media LLC

Subject

Obstetrics and Gynecology,General Medicine

Reference44 articles.

1. Koch-Institut R (2017) Krebs in Deutschland für 2013/2014. Robert Koch-Institut. https://doi.org/10.17886/rkipubl-2017-007

2. Colombo N, Creutzberg C, Amant F, Bosse T, Gonzalez-Martin A, Ledermann J, Marth C, Nout R, Querleu D, Mirza MR, Sessa C, Group E-E-EECCW (2016) ESMO-ESGO-ESTRO Consensus conference on endometrial cancer: diagnosis, treatment and follow-up. Int J Gynecol Cancer 26(1):2–30. https://doi.org/10.1097/IGC.0000000000000609

3. Hampel H, Frankel W, Panescu J, Lockman J, Sotamaa K, Fix D, Comeras I, La Jeunesse J, Nakagawa H, Westman JA, Prior TW, Clendenning M, Penzone P, Lombardi J, Dunn P, Cohn DE, Copeland L, Eaton L, Fowler J, Lewandowski G, Vaccarello L, Bell J, Reid G, de la Chapelle A (2006) Screening for Lynch syndrome (hereditary nonpolyposis colorectal cancer) among endometrial cancer patients. Cancer Res 66(15):7810–7817. https://doi.org/10.1158/0008-5472.CAN-06-1114

4. Buchanan DD, Tan YY, Walsh MD, Clendenning M, Metcalf AM, Ferguson K, Arnold ST, Thompson BA, Lose FA, Parsons MT, Walters RJ, Pearson SA, Cummings M, Oehler MK, Blomfield PB, Quinn MA, Kirk JA, Stewart CJ, Obermair A, Young JP, Webb PM, Spurdle AB (2014) Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing. J Clin Oncol 32(2):90–100. https://doi.org/10.1200/JCO.2013.51.2129

5. Berends MJ, Wu Y, Sijmons RH, van der Sluis T, Ek WB, Ligtenberg MJ, Arts NJ, ten Hoor KA, Kleibeuker JH, de Vries EG, Mourits MJ, Hollema H, Buys CH, Hofstra RM, van der Zee AG (2003) Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis. J Clin Oncol 21(23):4364–4370. https://doi.org/10.1200/JCO.2003.04.094

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