Acute hemodynamic effects of a new inotropic agent, OPC-8212, on severe congestive heart failure

Author:

Sasayama Shigetake,Inoue Michitoshi,Asanoi Hidetsugu,Kodama Kazuhisa,Hori Masatsugu,Sakurai Tsunetaro,Kawai Chuichi

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine

Reference17 articles.

1. Braunwald E, Colucci WS (1984) Evaluating the efficacy of new inotropic agents. J Am Coll Cardiol 3: 1570–1574

2. Packer M (1983) Vasodilator and inotropic therapy for severe chronic heart failure: Passion and skepticism. J Am Coll Cardiol 2: 841–852

3. Tominaga M, Yo E, Ogawa H, Yamashita S, Yabuuchi Y, Nakagawa K (1984) Studies on positive inotropic agents I. Synthesis of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone and related compounds. Chem Pharm Bull 32: 2100–2110

4. Yamashita S, Hosokawa T, Kojima M, Mori T, Yabuuchi Y (1984) In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone (OPC-8212), a novel positive inotropic drug, in various animals. Arzneim Forsch/Drug Research 34: 342–346

5. Taira N, Endoh M, Iijima T, Satoh K, Yanagisawa T, Yamashita S, Maruyama M, Kawada M, Morita T, Wada Y (1984) Mode and mechanism of action of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone (OPC-8212), a novel positive inotropic drug, on the dog heart. Arzneim Forsch/Drug Research 34: 347–354

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