Human metabolism of tolfenamic acid. II. Structure of metabolites and C-13 NMR assignments of fenamates-Reference-Cited by-同舟云学术

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Human metabolism of tolfenamic acid. II. Structure of metabolites and C-13 NMR assignments of fenamates

Published:1982-10 Issue:4 Volume:7 Page:269-276
ISSN:0378-7966
Container-title:European Journal of Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:European Journal of Drug Metabolism and Pharmacokinetics

Author:

Khalifah Raja G.,Hignite Charles E.,Pentikäinen Pertti J.,Penttilä Aneri,Neuvonen Pertti J.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

http://link.springer.com/content/pdf/10.1007/BF03189629.pdf

Reference9 articles.

1. Pentikäinen, P.J., Neuvonen, P.J. and Backman, C. (1981), Eur. J. Clin. Pharmacol., Human pharmacokinetics of tolfenamic acid, a new anti-inflammatory agent,19, 359–366.

2. Rejholec, V., Vapaatalo, H., Tokola, O., Gothoni, G. (1979), Scand. J. Rheum. (Suppl.), A comparative double-blind study on tolfenamic acid in the treatment of rheumatoid arthritis,24, 13–16.

3. Kauppila, A., Ylikorkala, O. (1977), Eur. J. Obst. Gynecol. Reprod. Biol., Indomethacin and tolfenamic acid in primary dysmenorrhea,7, 59–64.

4. Hakkarainen, H., Vapaatalo, H., Gothoni, G., Parantainen, J. (1979), Lancet, Tolfenamic acid is as effective as ergotamine during migraine attacks,2, 326–328.

5. Kajander, A., Martio, J., Mutru, O., Gothoni, G. (1976), Scand. J. Rheum., Prolonged treatment with tolfenamic acid in inflammatory rheumatic diseases,4, 158–160.

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3. Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs;Bioorganic & Medicinal Chemistry;2014-10

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