Genetic polymorphism of methylenetetrahydrofolate reductase (MTHFR) and coronary artery disease

Author:

Rassoul Fausi,Richter Volker,Kuntze Thomas,Mohr Friedrich-Wilhelm,Geisel Jürgen,Herrmann Wolfgang

Publisher

Georg Thieme Verlag KG

Subject

Cardiology and Cardiovascular Medicine

Reference17 articles.

1. Frosst P, Blom HJ, Milos R, et al (1995) A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. Nat Genet 17:195–200.

2. Graham IM, Daly LE, Refsum HM, et al (1997) Plasma homocysteine as risk factor for vascular disease. JAMA 277:1775–1781.

3. den Heijer M, Koster T, Blom HJ, et al (1996) Hyperhomocysteinemia a risk factor for deep-vein thrombosis. N Engl J Med 334:759–762.

4. Kang SS, Wong PW, Zhou J, et al (1988) Thermolabile methylenetetrahydrofolate reductase in patient with coronary artery disease. Metabolism 37:611–613.

5. Kluijtmans LA, van den Heuvel LP, Boers GH, et al (1996) Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hurn Genet 58:35–41.

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