Plasma pharmacokinetics of the antitumour agents 5,6-dimethylxanthenone-4-acetic acid, xanthenone-4-acetic acid and flavone-8-acetic acid in mice

Author:

McKeage Mark J.,Kestell Philip,Denny William A.,Baguley Bruce C.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference29 articles.

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2. Atwell GJ, Rewcastle GW, Baguley BC, Denny WA (1990) Potential antitumor agents: 60. Relationships between structure and in vivo colon 38 activity for 5-substituted xanthenone-4-acetic acids. J Med Chem 33: 1375

3. Bibby MC, Double JA, Loadman PM (1989) Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy. J Natl Cancer Inst 81: 216

4. Brodfuehrer J, Valeriote F, Chan K, Heilbrun L, Corbett T (1990) Flavone acetic acid and plasma protein binding. Cancer Chemother Pharmacol 27: 27

5. Chabot GG, Bissery M-C, Corbett TC, Rutkowski K, Baker LH (1989) Pharmacodynamics and causes of dose-dependent pharmacokinetics of flavone-8-acetic acid (LM-975; NSC-347 512) in mice. Cancer Chemother Pharmacol 24: 15

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