Novel HIF-1α Inhibitor AMSP-30m Mitigates the Pathogenic Cellular Behaviors of Hypoxia-Stimulated Fibroblast-Like Synoviocytes and Alleviates Collagen-Induced Arthritis in Rats via Inhibiting Sonic Hedgehog Pathway-Reference-Cited by-同舟云学术

Novel HIF-1α Inhibitor AMSP-30m Mitigates the Pathogenic Cellular Behaviors of Hypoxia-Stimulated Fibroblast-Like Synoviocytes and Alleviates Collagen-Induced Arthritis in Rats via Inhibiting Sonic Hedgehog Pathway

Published:2023-07-22 Issue:6 Volume:46 Page:2289-2305
ISSN:0360-3997
Container-title:Inflammation
language:en
Short-container-title:Inflammation

Author:

Cai Li,Meng Bo,Jiang Fei,Shu Wen-hao,Wang Xiao-hua,Wang Meng-qing,Wu Xin-jie,Hu Ming-wang,Yang Yu-chen,Ran Xiang,Li Rong

Funder

Anhui Provincial Natural Science Foundation

Open Project Program of Inflammation and Immune Mediated Diseases Laboratory of Anhui Province

Research Fund of Anhui Institute of Translational Medicine

National Natural Science Foundation of China

The University Synergy Innovation Program of Anhui Province

Scientific Research Level Promotion Program of Anhui Medical University

Undergraduate Innovation Training Program of Anhui Medical University

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

https://link.springer.com/content/pdf/10.1007/s10753-023-01878-3.pdf

Reference44 articles.

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3. Masoumi, M., H. Bashiri, H. Khorramdelazad, K. Barzaman, N. Hashemi, H.A. Sereshki, A. Sahebkar, and J. Karami. 2021. Destructive roles of fibroblast-like synoviocytes in chronic inflammation and joint damage in rheumatoid arthritis. Inflammation 44: 466–479.

4. Bartok, B., and G.S. Firestein. 2010. Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis. Immunological Reviews 233: 233–255.

5. Tsaltskan, V., and G.S. Firestein. 2022. Targeting fibroblast-like synoviocytes in rheumatoid arthritis. Current Opinion in Pharmacology 67: 102304.

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