Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators

Author:

Wang Xiaoshuang,Yang Liu,Yang Li,Xing Faping,Yang Hua,Qin Liyue,Lan Yunyi,Wu Hui,Zhang Beibei,Shi Hailian,Lu Cheng,Huang Fei,Wu Xiaojun,Wang Zhengtao

Funder

National Natural Science Foundation of China

Shanghai Sailing Program

Natural Science Foundation of Shanghai

Educational Commission of Shanghai in China

Shanghai E-Research Institute of Bioactive Constituent in TCM plan

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Reference37 articles.

1. Ballerini, P., F. Diomede, N. Petragnani, S. Cicchitti, I. Merciaro, Mfxb Cavalcanti, and O. Trubiani. 2017. Conditioned medium from relapsing-remitting multiple sclerosis patients reduces the expression and release of inflammatory cytokines induced by LPS-gingivalis in THP-1 and MO3.13 cell lines. Cytokine 96: 261–272. doi: 10.1016/j.cyto.2017.04.022 .

2. Berger, J.V., A.O. Dumont, M.C. Focant, M. Vergouts, A. Sternotte, A.G. Calas, S. Goursaud, and E. Hermans. 2012. Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes. Neuroscience 205: 29–38. doi: 10.1016/j.neuroscience.2011.12.044 .

3. Bozic, I., D. Savic, D. Laketa, I. Bjelobaba, I. Milenkovic, S. Pekovic, N. Nedeljkovic, and I. Lavrnja. 2015. Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia. PloS One 10 (2): e0118372. doi: 10.1371/journal.pone.0118372 .

4. Brambilla, R., T. Persaud, X. Hu, S. Karmally, V.I. Shestopalov, G. Dvoriantchikova, D. Ivanov, L. Nathanson, S.R. Barnum, and J.R. Bethea. 2009. Transgenic inhibition of astroglial NF-kappa B improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation. Journal of Immunology 182 (5): 2628–2640. doi: 10.4049/jimmunol.0802954 .

5. Cai, H., Q. Liang, and G. Ge. 2016. Gypenoside attenuates beta amyloid-induced inflammation in N9 microglial cells via SOCS1 signaling. Neural Plasticity 2016: 6362707. doi: 10.1155/2016/6362707 .

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