Amitriptyline Downregulates Chronic Inflammatory Response to Biomaterial in Mice

Author:

Scheuermann Karina,Orellano Laura Alejandra Ariza,Viana Celso Tarso Rodrigues,Machado Clara Tolentino,Lazari Marcela Guimarães Takahashi,Capettini Luciano Santos Aggum,Andrade Silvia Passos,Campos Paula PeixotoORCID

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Reference42 articles.

1. Xia, Brent T., Nadine Beckmann, Leah K. Winer, Young Kim, Holly S. Goetzman, Rosalie E. Veile, Erich Gulbins, Michael D. Goodman, Vanessa Nomellini, and Charles C. Caldwell. 2019. Amitriptyline treatment mitigates sepsis-induced tumor necrosis factor expression and coagulopathy. Shock 51: 356–363. https://doi.org/10.1097/SHK.0000000000001146.

2. Vismari, Luciana, Glaucie J. Alves, Marcelo N. Muscará, and João Palermo-Neto. 2012. A possible role to nitric oxide in the anti-inflammatory effects of amitriptyline. Immunopharmacology and Immunotoxicology 34: 578–585. https://doi.org/10.3109/08923973.2011.638305.

3. Hajhashemi, Valiollah, Hossein Sadeghi, Mohsen Minaiyan, Ahmad Movahedian, and Ardeshir Talebi. 2010. The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats. Clinics 65: 1183–1187. https://doi.org/10.1590/S1807-59322010001100022.

4. Fattahian, Ehsan, Valiollah Hajhashemi, Mohammad Rabbani, Mohsen Minaiyan, and Parvin Mahzouni. 2016. Anti-inflammatory effect of amitriptyline on ulcerative colitis in normal and reserpine-induced depressed rats. Iranian Journal of Pharmaceutical Research 15: 125–137. https://doi.org/10.22037/ijpr.2016.1813.

5. Manning, Jennifer, Rebecca Kulbida, Prerana Rai, Lindsay Jensen, Judith Bouma, Sanjay P. Singh, D. O’Malley, and Deniz M. Yilmazer-Hanke. 2014. Amitriptyline is efficacious in ameliorating muscle inflammation and depressive symptoms in the mdx mouse model of Duchenne muscular dystrophy. Experimental Physiology 99: 1370–1386. https://doi.org/10.1113/expphysiol.2014.079475.

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