Inhibition of Dyrk1A Attenuates LPS-Induced Neuroinflammation via the TLR4/NF-κB P65 Signaling Pathway
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
https://link.springer.com/content/pdf/10.1007/s10753-022-01699-w.pdf
Reference36 articles.
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2. Dierssen, M., and M.M. de Lagrán. 2006. DYRK1A (dual-specificity tyrosine-phosphorylated and -regulated kinase 1A): A gene with dosage effect during development and neurogenesis. The Scientific World Journal 6: 1911–1922. https://doi.org/10.1100/tsw.2006.319.
3. Guedj, F., P.L. Pereira, S. Najas, M.J. Barallobre, C. Chabert, B. Souchet, C. Sebrie, C. Verney, Y. Herault, M. Arbones, and J.M. Delabar. 2012. DYRK1A: A master regulatory protein controlling brain growth. Neurobiology of Diseases 46: 190–203. https://doi.org/10.1016/j.nbd.2012.01.007.
4. Velazquez, R., B. Meechoovet, A. Ow, C. Foley, A. Shaw, B. Smith, S. Oddo, C. Hulme, and T. Dunckley. 2019. Chronic Dyrk1 inhibition delays the onset of AD-like pathology in 3xTg-AD mice. Molecular Neurobiology 56: 8364–8375. https://doi.org/10.1007/s12035-019-01684-9.
5. Shi, J., T. Zhang, C. Zhou, M.O. Chohan, X. Gu, J. Wegiel, J. Zhou, Y.W. Hwang, K. Iqbal, I. Grundke-Iqbal, et al. 2008. Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome. Journal of Biological Chemistry 283: 28660–28669. https://doi.org/10.1074/jbc.M802645200.
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